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The phenolic hydroxyl group contributes additional hydrogen bonding capacity, while the aliphatic chain increases hydrophobic character relative to shorter peptide analogues

359 Antioxidants also modulate ferroptosis in RA

While these preclinical findings are promising, chrysin holds similar limitations as the rest of the flavonoids, such as poor bioavailability due to a low water solubility of 0.005 mg/mL which limits its application [146]

This apparent lack of a global reactive astrogliosis response was not anticipated based on prior studies using a controlled cortical impact paradigm to induce TBI

Microglia have two activation states that have opposing roles in brain metastases