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Enhanced DRP1 phosphorylation, for instance, causes excessive mitochondrial fragmentation, generating dysfunctional fragments that leak ROS (OH) and mtDNA, activating inflammasomes and apoptotic signals [203]

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Peroxyl Radical Scavenging Activity Measurement of Antioxidants Using HistidineStabilized and GlutathioneCapped Fluorescent Gold Nanoclusters. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 285: 121876

None of these factors alone necessarily causes TMD