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Clinical trials of GLP-1 receptor agonists have shown average reductions in daily energy intake of roughly 2030% during early treatment phases , reflecting the combined effects of increased satiety and reduced food preoccupation

[15] [16] While their efficacy in achieving significant weight reduction is well-established, understanding their complete safety profileincluding potential neurological effectsremains essential for both clinicians and patients

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Iovino M., et al

Addressing this side effect would substantially improve the feasibility of employing GLP-1 analogs for opioid withdrawal treatment
